Listar por autor "Sivridis, E."
Mostrando ítems 1-16 de 16
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Angiogenesis and apoptosis-related protein (p53, bcl-2, and bax) expression versus response of gastric adenocarcinomas to paclitaxel and carboplatin chemotherapy
Giatromanolaki, A.; Stathopoulos, G. P.; Koukourakis, M. I.; Rigatos, S.; Vrettou, E.; Kittas, C.; Fountzilas, G.; Sivridis, E. (2001)The role of angiogenesis and apoptosis-related proteins in defining response to chemotherapy is poorly understood. We examined the microvessel density (MVD) and the expression of p53, bcl-2, and bax proteins in a series ... -
Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy
Koukourakis, M. I.; Giatromanolaki, A.; Fountzilas, G.; Sivridis, E.; Gatter, K. C.; Harris, A. L. (2000)Thymidine phosphorylase (TP), an enzyme involved in the thymidine synthesis and degradation, has been shown to promote tumor angiogenesis, Both TP expression and tumor vascularization are putative postoperative prognostic ... -
Angiogenic interactions of vascular endothelial growth factor, of thymidine phosphorylase, and of p53 protein expression in locally advanced gastric cancer
Giatromanolaki, A.; Koukourakis, M. I.; Stathopoulos, G. P.; Kapsoritakis, A.; Paspatis, G.; Kakolyris, S.; Sivridis, E.; Georgoulias, V.; Harris, A. L.; Gatter, K. C. (2000)The assessment of the angiogenic profile of tumors may become an important tool as a guide for the inclusion of novel drugs and molecular therapies into the standard chemoradiotherapy policy. Several studies have shown the ... -
The angiogenic pathway 'vascular endothelial growth factor/flk-I (KDR)-receptor' in rheumatoid arthritis and osteoarthritis
Giatromanolaki, A.; Sivridis, E.; Atanassou, N.; Zois, E.; Thorpe, P. E.; Brekken, R. A.; Gatter, K. C.; Harris, A. L.; Koukourakis, I. M.; Koukourakis, M. I. (2001)Active angiogenesis, together with an up-regulation of angiogenic factors, is evident in the synovium of both rheumatoid arthritis (RA) and osteoarthritis (OA). The present study assessed, by immunohistochemistry, the ... -
Bax protein expression in colorectal cancer: Association with p53, bcl-2 and patterns of relapse
Giatromanolaki, A.; Sivridis, E.; Stathopoulos, G. P.; Fountzilas, G.; Kalofonos, H. P.; Tsamandas, A.; Vrettou, E.; Scopa, C.; Polychronidis, A.; Simopoulos, K.; Koukourakis, M. I. (2001)This study evaluated the frequency and the prognostic significance of bax, bcl-2 and p53 proteins in stage B and C adenocarcinomas of the colon and rectum. Paraffin-embedded specimens from 268 patients with colorectal ... -
Cancer vascularization: Implications in radiotherapy?
Koukourakis, M. I.; Giatromanolaki, A.; Sivridis, E.; Fezoulidis, I. (2000)Purpose: Although hypoxia is considered a major cause of failure of radiotherapy, the mechanisms of tumor hypoxia are unclear, and effective ways for its correction or targeting are missing. Tumoral vasculature is the ... -
Chemopreventive activity of very low dose dietary tannic acid administration in hepatoma bearing C3H male mice
Nepka, C.; Sivridis, E.; Antonoglou, O.; Kortsaris, A.; Georgellis, A.; Taitzoglou, I.; Hytiroglou, P.; Papadimitriou, C.; Zintzaras, I.; Kouretas, D. (1999)Tannins are plant polyphenols comprising a heterogeneous group of compounds. Tannic acid is a common tannin found in tea, coffee, immature fruits, etc. and it has also been used as a food additive. An increasing body of ... -
Coexpression of MUC1 glycoprotein with multiple angiogenic factors in non-small cell lung cancer suggests coactivation of angiogenic and migration pathways
Giatromanolaki, A.; Koukourakis, M. I.; Sivridis, E.; O'Byrne, K.; Cox, G.; Thorpe, P. E.; Gatter, K. C.; Harris, A. L. (2000)We investigated the expression of MUC1 protein and its relationship to the microvessel density and the expression of thymidine phosphorylase, vascular endothelial growth factor (VEGF), VEGF-receptor KDR, basic fibroblast ... -
Effects of melatonin on proliferation of cancer cell lines
Papazisis, K. T.; Kouretas, D.; Geromichalos, G. D.; Sivridis, E.; Tsekreli, O. K.; Dimitriadis, K. A.; Kortsaris, A. H. (1998)The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x ... -
Endometrial carcinoma: association of steroid hormone receptor expression with low angiogenesis and bcl-2 expression
Sivridis, E.; Giatromanolaki, A.; Koukourakis, M.; Anastasiadis, P. (2001)In endometrial tissues, malignant change may be accompanied by a loss of hormone dependence which is, usually, reflected in a parallel loss of oestrogen and progesterone receptors (ER and PR). In this study, the steroid ... -
Expression of 6 Common Antigenic Markers in Invasive Ductal Breast Carcinoma: Potential Clinical Implications
Lialiaris, T. S.; Kouskoukis, A.; Georgiou, G.; Tripsianis, G.; Fiska, A.; Giatromanolaki, A.; Chrisafi, S.; Sivridis, E.; Vamvakopoulou, D. N.; Soutopoulou, D. O.; Kiritsaka, A.; Athanassiou, E.; Lialios, G. A.; Sotiriou, S.; Sidiropoulos, A.; Vamvakopoulos, N. C. (2011)Expression of estrogen (ER) and progesterone receptors, c-erbB-2 oncogene, mutant p53 antioncogene (mp53), e-cadherin adhesion, and apoptotic caspase-8 antigens in tumor relative to matched normal tissue specimens from 102 ... -
'Invading edge vs. inner' (edvin) patterns of vascularization: an interplay between angiogenic and vascular survival factors defines the clinical behaviour of non-small cell lung cancer
Giatromanolaki, A.; Koukourakis, M. I.; Sivridis, E.; O'Byrne, K.; Gatter, K. C.; Harris, A. L. (2000)Neo-angiogenesis during neoplastic growth involves endothelial mitogenic and migration stimuli produced by cancer or tumour stromal cells. Although this active angiogenesis takes place in the tumour periphery, the process ... -
Prognostic role of angiogenesis in operable carcinoma of the gallbladder
Giatromanolaki, A.; Sivridis, E.; Koukourakis, M. I.; Polychronidis, A.; Simopoulos, C. (2002)The prognostic significance of intratumoral angiogenesis was investigated in 62 patients with stage I-III carcinomas of the gallbladder treated with simple cholecystectomy. Microvessel density (MVD) was assessed ... -
Thymidine phosphorylase expression in normal and hyperplastic endometrium
Sivridis, E.; Giatromanolaki, A.; Koukourakis I, M.; Bicknell, R.; Harris, A. L.; Gatter, K. C. (2000)Aims - To investigate the expression of thymidine phosphorylase (TP), a known angiogenic factor for endothelial cells, in normally cycling endometrium and various forms of endometrial hyperplasia. Methods - TP expression ... -
Treatment of Low-risk Prostate Cancer with Radical Hypofractionated Accelerated Radiotherapy with Cytoprotection (HypoARC): An Interim Analysis of Toxicity and Efficacy
Koukourakis, M. I.; Kyrgias, G.; Papadopoulou, A.; Panteliadou, M.; Giatromanolaki, A.; Sivridis, E.; Mavropoulou, S.; Kalogeris, K.; Nassos, P.; Milioudis, N.; Touloupidis, S. (2011)Aim: Radiobiological analysis of clinical data suggests that prostate cancer has a low alpha/beta ratio, implying that large radiotherapy fractions may better control the disease. Acceleration of radiotherapy may be also ... -
Tumor angiogenesis is associated with MUC1 overexpression and loss of prostate-specific antigen expression in prostate cancer
Papadopoulos, I.; Sivridis, E.; Giatromanolaki, A.; Koukourakis, M. I. (2001)The biological potential of prostate cancer is highly variable and cannot be satisfactorily predicted by histopathological criteria alone. Therefore, additional and more precise information is desirable. Although angiogenesis ...